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|Timeline for 1665|
• 1660 • 1661 • 1663 • 1666 • 1669 • 1671
In 1665, the first cases of what would become known as the Great Plague of London appeared on the city's outskirts. The disease became more widespread and fatal the following year, after a deadlier strain of the bacterium Yersinia pestis was engineered by a group of escaped Terileptil criminals. It killed an estimated 100,000 people.Fifth Doctor and Nyssa visited Suffolk. (AUDIO: The Demons of Red Lodge)