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Alpha Centauri — or permeations thereupon — may refer to:
- Alpha Centauri (The Curse of Peladon), the Galactic Federation ambassador and friend of the Doctor.
- Alpha Centauran, the species the ambassador counted themself among.
- Alpha Centauri (planet). the home planet of the Alpha Centaurans.
- Alpha Centauri (system), the star system the planet Alpha Centauri belonged to.
- The Alpha Centauran Table Tennis Club