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Anna Frobisher was the wife of John Frobisher and the mother of Holly and Lilly Frobisher. When the 456 took over the children at 8:40 a.m in September 2009, neither her husband nor she noticed their daughters had stopped. When Mr Frobisher got home, their daughters were saying "we are coming" and Anna broke down. (TV: Children of Earth: Day One)

John killed Anna, Lilly, Holly and then himself after the Prime Minister Brian Green told him to give his daughters to the 456 to maintain the government's inoculation cover story as they tried to hand over 10% of Britain's children. (TV: Children of Earth: Day Five)