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Arabella Weir played an alternative, alcohol-addled female version of the Doctor in Exile, part of the Doctor Who Unbound series of audio adventures produced by Big Finish Productions. She and Joanna Lumley are the only two women to play the Doctor in a BBC-licensed production. Weir is to date the only American-born actor to portray the character — although she is not considered an American.
The daughter of former British ambassador Sir Michael Weir, she is a famous for her roles in The Fast Show (alongside Mark Williams) and books including Does My Bum Look Big In This? (a catchphrase of one of her characters in the show) and Onwards and Upwards, first published in 1999. Arabella also writes articles for The Guardian periodically. These articles, although mainly about recent events, commonly include details regarding Arabella's life and the things that she considers to be pestiferous.
Weir wrote and starred in the 2003 comedy series Posh Nosh, co-starring Richard E Grant. David Tennant made a few guest appearances in that series as well. She contributes to the popular BBC2 comedy series, Grumpy Old Women.
She is married to Dr Jeremy Norton, and they have two children. David Tennant is a long-term friend of Weir's, and is godfather to their youngest child. He and Weir met in 1994 when they acted in the Scottish TV series Takin' Over the Asylum together, and when Tennant moved to London the following year, he moved into Weir's house, being her lodger for several years.