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In 1945, Hiroshima and Nagasaki were hit by atomic bombs. These events caused the Japanese to surrender to the Allies, thus ending the Second World War. A third bomb was planned to be dropped on Kyoto, but the aircraft carrying the bomb, the Sky Jack, fell through a black hole. (COMIC: Sky Jacks)
As Butler professed in an indoctrination film shown to Sarah Jane Smith, humanity was capable, with the development of the atomic bomb, of destroying the whole planet very quickly in a nuclear war. (TV: Invasion of the Dinosaurs)
According to the Third Doctor, if Wenley Moor nuclear research facility were not able to stabilise in time for power outages caused by the Silurians, their nuclear reactor could potentially "turn into a massive atomic bomb". (TV: Doctor Who and the Silurians)