Since the 25 April 1964 premiere of "The Screaming Jungle", it has been the network of origin for Doctor Who, excepting a few unusual stories, such as The Five Doctors and the 1996 telemovie. It was also the home network for A Girl's Best Friend, Invasion of the Bane, and the third series of Torchwood.
Doctor Who premiered on the BBC in 1963 with An Unearthly Child. During broadcast of the fifth storyline, The Keys of Marinus, the BBC launched a new network, BBC Two. Beginning with the third episode of Marinus, "The Screaming Jungle", Doctor Who was said to air on BBC One.
BBC One has also been the home network of several (but not all) Doctor Who spinoff productions.
- A Girl's Best Friend, the pilot (and only episode of) K9 and Company in 1981.
- Totally Doctor Who, a programme for younger viewers devoted to the franchise. During series 2, an animated serial, The Infinite Quest, was broadcast as part of this series.
- Invasion of the Bane, the first episode (also referred to as the pilot) of The Sarah Jane Adventures, aired on BBC One in January 2007. The subsequent series aired on CBBC, a spin-off network, but were later replayed by BBC One, usually a week later.
- Series 3 of Torchwood, the Children of Earth miniseries, aired on BBC One in July 2009. The first two seasons aired on BBC Three and BBC Two, respectively.
- Series 4 of Torchwood, entitled Torchwood: Miracle Day, aired on BBC One in Summer 2011. Episodes were shown on Thursday nights a few days after their premiere in America on Starz.