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The Czech Republic was a country in Europe. It broke away from Czechoslovakia at some point in the late 20th century, as did Slovakia. Its capital city, Prague, was visited by the Doctor in most of his incarnations. (PROSE: Life from Lifelessness, Spoilsport, The Dragons of Prague, Suspension and Disbelief, Leap Second, Sunday Afternoon, AD 848,988, Fable Fusion, War in a Time of Peace; COMIC: The Broken Man)

InterCom had research facilities in the Czech Republic. There, they had been looking, unsuccessfully, for human candidates that possessed DNA appropriately resistant to their late-1990s DNA-extraction project headed by Chung Sen. (PROSE: The King of Terror)

In August 2016, Mickey Smith was busy doing something in the Czech Republic while his wife Martha Jones investigated the Gargoyles in San Francisco. (COMIC: The Transformed)

In the 23rd century, Slovakia and Czechia were again united as the Third Czech and Slovak Republic. (PROSE: Spoilsport)

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