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Distronic toxaemia was a disorder that quickly caused fatigue and killed whomever developed it in a short period of time. It could be caused by exposure to distronic explosives, which were usually used in explosive rockets. Near the end of the Thousand Year War on Skaro, the Thals developed a rocket with a distronic warhead to destroy the Kaled Dome. The Thals used an expendable slave labour force, including Sarah Jane Smith and Sevrin, to load the dangerous element into the warhead. (TV: Genesis of the Daleks)