Masters visited the Wenley Moor nuclear research facility when a series of power drains and mental breakdowns were caused by the Silurians, whom had recently been awakened from their hibernation units. During his visit, the station security chief, Major Baker, was infected with the Silurian virus. Masters left before the base was quarantined, unaware of being infected himself.
The day before his death, Masters had been scheduled to give an interview to the journalist James Stevens of the Daily Chronicle but had to cancel when he was called to the nuclear research facility. (PROSE: Who Killed Kennedy)
Behind the scenes
In the novel Who Killed Kennedy, Edward Masters, as he is known from his first appearance in the TV story Doctor Who and the Silurians, is called Frederick Masters (he is also called Frederick in the novelisation of the TV story). Although in the novelisation, Masters retains his role of Permanent Under Secretary, he is somewhat confusingly called a Member of Parliament and not a civil servant.