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The Eye of Disharmony was a superweapon created by the Threshold in the town of Wormwood on the Moon in the 53rd century. It had the appearance of an upside-down, four-sided pyramid with an eye on it.

The Threshold activated it and "destroyed outer space". The blackness of the universe became white and all ships that were not within a planet's atmosphere at the time of activation were destroyed. The Threshold planned to sell transportation to the universe, but the Doctor[which?] defeated them, and space was reverted back to normal, destroying the Moon in the process. (COMIC: Wormwood)

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