High Wycombe was a town, located in the south of England. (TV: The Categories of Life) It was founded circa 1760. (PROSE: Return of the Spiders)
In the late 20th century, the Fourth Doctor, Romana and K9 visited High Wycombe, where they defeated the Queen Spider's plans to conquer Earth. (PROSE: Return of the Spiders)
During Miracle Day in 2011, an overflow camp was set up in or around High Wycombe. (TV: The Categories of Life)