Kirsten O'Brien was the second and final female presenter on Totally Doctor Who. She appeared in series 2 of the kids' version of Doctor Who Confidential, broadcast alongside the third series of Doctor Who. She was later the presenter of Inside the World of Doctor Who, a one-off BAFTA event that was in many ways a live version of Totally.

Following the cancellation of Totally she was much in demand as a presenter and sometime celebrity guest. She has been used repeatedly by the production staff of EastEnders as a narrator of documentaries about that franchise.

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