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Klyst was a director of the Klyst Institute. She tried to get through the Seventh Doctor's post regenerative madness to get to the real him. She wanted to cure the Doctor. She used to talk to him about the goings on. She wished that they had Dalek mutants to work on. She was planting AIs into the patients so they would use have an affinity with Block Transfer Computation, and trying to stop the AIs breaking down. (AUDIO: Unregenerate!)

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