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Nuclear power was a form of energy, usually produced in nuclear power plants. According to the Second Doctor, to obtain nuclear power, one had to split the atom; the principal element used for this was uranium. (COMIC: Atoms Infinite)
In the early 21st century, Victoria Waterfield became involved in the protests against nuclear energy. At that time, she was reunited with the Doctor, by then in his sixth incarnation, and met his latest companion, Peri Brown. (AUDIO: Power Play)
Wanda Rothman and her team discovered vodium, which she believed could be used as a source of low-waste nuclear energy. In 2010 she was at a conference to show off the vodium. During the demonstration she accidentally activated it, which caused it to produce micro-wormholes. These wormholes started pulling in people from the hotel, though she didn't realise the connection. Once the Eighth Doctor revealed the truth, she helped him neutralise the vodium. (AUDIO: Situation Vacant)