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An optic nerve was an organ related to sight. (TV: Flatline) Optic nerves could misfire, resulting in temporary or even permanent blindness. (PROSE: The Door into Bedlam)

The Twelfth Doctor once hacked Clara Oswald's optic nerve using nanotech, allowing him to see whatever she saw, on the TARDIS monitor. (TV: Flatline) When one's optic nerve was "tapped", though, the act could leave behind scars on the supra-orbital ridge, above the eye. (PROSE: War Crimes)

The Half-Face Man burned a dinosaur that appeared in the River Thames, to use its optic nerve to repair the Clockwork Droids' ship, the SS Marie Antoinette. (TV: Deep Breath)

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