The personal destructor was a weapon used by the Angvians. It was composed of modulated black star matter within a tasteless pill. When swallowed, the pill would attach itself to the host's digestive tract, eventually activating when sufficiently stressed. It would then explode with the force of thousands of scatter bombs.
While trying to block the peace treaty between the Angvians and Gholos, Loozly obtained a personal destructor so the Angvians would be blamed. He had Nicky Newman swallow it unknowingly, with it activating when he was nervous. Loozly was stopped, though, and the personal destructor was removed by Dr Eleanor Harcourt. (AUDIO: Bang-Bang-a-Boom!)