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In the 38th century, Professor Gagan Rassmussen's experiments with improving Morpheus pods resulted in the creation of life-forms made of sleep dust, which Clara Oswald dubbed "Sandmen". (TV: Sleep No More)
The Eighth Doctor thought that the diamond-like object (actually the Master's trap) he found in the corner of the Eye of Harmony was irritating the Eye like "sleep" did to human eyes. (PROSE: The Eight Doctors)