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Mistress or the Mistress refers to several characters.
- The Mistress, a character in AUDIO: The Choice and The Search.
- The Mistress, a character in TV: Warriors of Kudlak.
- Missy (short for "the Mistress"), the female incarnation of the Master, who debuted in TV: Deep Breath.
- "Mistress" was a general form of address used by various models of K9 toward female allies including Leela, Romana, and Sarah Jane Smith.