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The Twelve Galaxies was a regional or political group of galaxies that was occationally mentioned at different times. The Cat-People spread across the Twelve Galaxies when, during an energy crisis, they were called back to the litter-world Feles. (PROSE: Invasion of the Cat-People)

Around the year 2,000,000, this region might have possibly contained the planets Proamon and Svartos. Kane offered Ace the chance to join him, saying that Twelve Galaxies could be hers. The Seventh Doctor later offered to take her on a trip around the Twelve Galaxies before taking her home to Perivale. (TV: Dragonfire)

Irving Braxiatel wrote legislation to prohibit the use of Time Scoops throughout the Twelve Galaxies. (AUDIO: Panacea)

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